EKN 30th Anniversary  December 8, 2000

10.00 – 10.15     Opening EKN 30th Anniversary symposium (Peter De Deyn)

10.15 – 10.35     The use of microdialysis in experimental neuropharmacology (Guy Ebinger)
10.35 – 10.47    Investigation of the pharmacodynamic effects and the pharmacokinetic properties of Galantamine in the brain of conscious, freely rats moving by means of microdialysis (Dieter Scheller)
10.47 – 11.00     Mechanism-based pharmacokinetic and -pharmacodynamic analysis of the GABA-A receptor mediated EEG effects of neuroactive steroids and benzodiazepines in rats (Sandra Visser)
11.00 – 11.12     Impact of the blood-brain barrier on distribution of drugs into the CNS (Liesbeth de Lange)
11.12 – 11.25     Intercellular calcium signalling at the blood-brain barrier: mechanisms and possible functions (Luc Leybaert)
11.25 – 11.37     S100A6, a calcium and zinc binding protein, is overexpressed in SOD1 mutant mice, a model for ALS (Roland Pochet)
11.37 – 11.50     Ca2+ signalling and in vitro neuroprotection properties of glutamate receptor antagonists: implications for stroke therapy (Anne Lesage)
11.50 – 12.02     Antagonist-mediated enhancement of mGluR1 signalling (Hilde Lavreysen)

12.02 – 12.30     Poster session
12.30 – 13.00     Lunch
13.00 – 14.00     Social Session: career paths

 Business meeting (members)

14.00 – 14.10     Announcement of the Poster Prize (Peter De Deyn)

14.10 – 14.30     From glucose to glucocorticoids (Ron de Kloet)
14.30 – 14.50     Gender and chronic stress: implications for aetiology of mood disorders (Gert ter Horst)
14.50  – 15.00    Different forms of stress alter prepulse inhibition in APO-SUS and APO-   UNSUS rats (Thomas Sontag).
15.00 – 15.10     Electrical stimulation of the brain in animal models for one or more of the symptoms of obsessive-compulsive disorder (Hilde Demeulemeester)
15.10 – 15.30     The beneficial antidepressant effects of co-administration of pindolol with SSRIs is not related to 5-HT1A antagonism (Thomas Cremers)
15.30 – 15.50     Postsynaptic 5-HT1A receptor mediated feedback (Fokko Bosker)
15.50 – 16.10     Serotonin binding proteins: from serotonin storage to an in vitro model for neurotoxicity (Georges Vauquelin)
16.10 – 16.30     Neuroregeneration (Gerard Boer)

16.30 – 16.45 Coffee break

16.45 – 17.00     Announcement of the EKN Innovation Prize for Neuroscience (Peter De Deyn and Willem Hendrik Gispen)
17.00 – 18.00     Innovation Lecture: The secretases; novel molecular targets for drug design in the fight against Alzheimer's disease (Bart De Strooper)
18.00 – 18.10     Closing remarks (Peter De Deyn)
18.10 – 20.00     Reception